Adults living alone faced a higher risk of death from a range of causes than adults who shared a home, according to a large study from the American Cancer Society published in the International Journal of Epidemiology. The gap was widest for adults aged 18 to 64, whose overall risk of death ran 22% higher, compared with 6% higher for adults aged 65 and older.

Solo households have become far more common in the United States since the late 1960s. The share of people in single-person households rose from 7.6% in 1967, when 9.4 million people lived that way, to 14.8% in 2023, when the figure reached 38.1 million, researchers said in background notes accompanying the study. For the new analysis, researchers drew on nearly six hundred thousand adults whose survey answers were matched against death records covering 1998 to 2018, giving roughly two decades of follow-up.

The findings cut against a common assumption that isolation is mainly a health threat for older people. In this data, the younger and middle-aged group carried the larger overall increase, while older adults showed a smaller overall rise but a much sharper increase for one cause in particular. The pattern held across a long list of causes of death, and the researchers said the explanation lay less in the household arrangement itself than in the health habits and circumstances that often go with it.

The sharpest risks were for younger adults

Among adults in the younger group, solo living was tied to a 58% higher risk of dying by suicide, a 41% higher risk of dying from heart disease, and a 34% higher risk of dying from diabetes, the study found. Colorectal cancer deaths ran 27% higher in the same group, cerebrovascular disease deaths ran 23% higher, and deaths from accidents ran 17% higher, while deaths from all injuries combined ran more than a quarter higher.

For older adults, the picture looked different. Suicide deaths ran 103% higher among those on their own, the steepest single increase in the study, while deaths attributed to high blood pressure ran 28% higher, heart disease deaths ran 11% higher, and injury deaths ran 16% higher. Suicide stood out as the leading cause of excess death in both age groups, researchers said, and colorectal cancer emerged as a notable driver of the gap for the younger group.

The study was reported on October 30 by HealthDay via Drugs.com, based on the American Cancer Society release and the journal paper. According to the American Cancer Society, the work used data from the National Health Interview Survey linked to the National Death Index, and the authors calculated hazard ratios for death from a range of specific causes. The paper was authored by Hyunjung Lee and colleagues, with Lee, principal scientist of cancer disparity research at the society, as lead author.

Why the gap exists

Lee said solo living was not necessarily harmful in itself, nor a poor arrangement, and stressed that the excess deaths were largely concentrated among people who already had existing health conditions and high-risk health exposures. In other words, the household arrangement coincided with other risks rather than acting on its own. People on their own were more likely to smoke and to drink heavily, the researchers wrote, and tended to eat saltier and less healthy food while making fewer visits to a doctor or for health examinations.

Those differences explained much of the gap. Differences in background, lifestyle, access to care, and existing health conditions accounted for 57% of the difference in overall death risk for the younger group and 85% of the difference for the older group, the team reported. That leaves a substantial share explained by factors the study could measure, and points to practical ground where support could make a difference: help with quitting smoking, steadier access to care, and attention to conditions that might otherwise go unmanaged when nobody else is in the home to notice a change.

The study design also sets limits on what can be claimed. It was an observational analysis of survey and death records, so it shows an association between household arrangement and later death, not proof that household arrangement causes death. The authors did not argue that everyone in a single-person household faces the same risk, and the concentration of excess deaths among people with existing conditions underlines that point. Readers looking for wider health context can also follow recent coverage of the early flu season and vaccine research on genznewz, including the early flu season report and the Sanofi combination vaccine trial.

What researchers say should change

Lee called, in a statement from the society, for policy and clinical efforts to identify modifiable risk factors behind the higher death risk for people in single-person households, including chronic disease management, injury prevention, improved access to preventive care, and screening for mental health conditions. The argument, as the researchers framed it, is that support should be aimed at the people most likely to benefit: those whose health is already fragile, whose habits carry added risk, or whose contact with care is thin.

That approach could take several concrete forms. Regular check-ins and community contact can catch a deteriorating condition sooner. Screening in primary care can pick up depression, diabetes, or heart risk before a crisis. Injury prevention, from safer homes to support after a fall, matters more when a person has nobody nearby to raise the alarm. None of those steps requires treating solo living itself as a problem to be fixed, and the researchers were clear that it should not be treated that way.

For now, the study adds weight to a growing body of work on how household structure shapes health, and it reframes the question for health services. The challenge is not the front door closing on a single occupant. It is whether that occupant has care, contact, and support close at hand when health starts to slip, and whether the system notices in time.